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High Genetic Barrier Considerations | SYMTUZA® (darunavir/cobicistat/emtricitabine/tenofovir alafenamide) HCP

Patients at Risk: HGBR

Do These Patient Factors Impact Your ARV Choice?

Patient silhouette

HIGH GENETIC BARRIER CONSIDERATIONS

Clinical:

  • Compliance risk unknown (eg, rapid initiation, new to you, uncertain adherence)
  • Young, with no experience with chronic medication
  • Prior low-level viremia

Lifestyle/Attitude:

  • Busy, irregular schedule (eg, flight attendant, shift work, night classes)
  • Psychosocial issues (eg, unstable housing, unemployment, lack of social support)

 

ARV=antiretroviral; HGBR=high genetic barrier to resistance.

Reference: Department of Health and Human Services. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. Updated January 20, 2022. Accessed March 8, 2022. https://clinicalinfo.hiv.gov/en/guidelines/adult-and-adolescent-arv/whats-new-guidelines

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